Nan Wu Selected Research

secretin receptor

1/2023	Knockout of secretin ameliorates biliary and liver phenotypes during alcohol-induced hepatotoxicity.
1/2023	Prolonged administration of a secretin receptor antagonist inhibits biliary senescence and liver fibrosis in Mdr2 -/- mice.
10/2021	Inhibition of Secretin/Secretin Receptor Axis Ameliorates NAFLD Phenotypes.
1/2019	Secretin/secretin receptor signaling mediates biliary damage and liver fibrosis in early-stage primary biliary cholangitis.
11/2018	Knockout of secretin receptor reduces biliary damage and liver fibrosis in Mdr2-/- mice by diminishing senescence of cholangiocytes.
10/2018	The Secretin/Secretin Receptor Axis Modulates Ductular Reaction and Liver Fibrosis through Changes in Transforming Growth Factor-β1-Mediated Biliary Senescence.
1/2016	The secretin/secretin receptor axis modulates liver fibrosis through changes in transforming growth factor-β1 biliary secretion in mice.

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Nan Wu Research Topics

Disease

154	Neoplasms (Cancer) 05/2024 - 07/2003
38	Fibrosis (Cirrhosis) 01/2024 - 09/2009
36	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 05/2024 - 10/2007
36	Neoplasm Metastasis (Metastasis) 02/2024 - 07/2002
36	Inflammation (Inflammations) 10/2023 - 10/2007
28	Breast Neoplasms (Breast Cancer) 03/2024 - 04/2010
27	Liver Cirrhosis (Hepatic Cirrhosis) 01/2023 - 09/2009
24	Lung Neoplasms (Lung Cancer) 01/2024 - 07/2005
18	Infections 03/2024 - 04/2006
18	Carcinogenesis 01/2024 - 07/2003
18	Hypoxia (Hypoxemia) 03/2022 - 01/2011
18	Myocardial Infarction 02/2021 - 01/2014
17	Reperfusion Injury 02/2021 - 01/2014
13	Cardiovascular Diseases (Cardiovascular Disease) 04/2024 - 02/2014
13	Adenocarcinoma of Lung 01/2024 - 04/2013
13	Pain (Aches) 01/2024 - 12/2006
12	Stomach Neoplasms (Stomach Cancer) 02/2024 - 06/2018
11	Ischemia 02/2021 - 07/2009
10	Wounds and Injuries (Trauma) 04/2024 - 10/2007
10	Colorectal Neoplasms (Colorectal Cancer) 02/2023 - 02/2004
10	Cholestasis 01/2023 - 01/2016
10	Hepatocellular Carcinoma (Hepatoma) 08/2022 - 07/2013
10	Myocardial Ischemia (Ischemic Heart Diseases) 02/2021 - 01/2014
10	Infarction (Infarctions) 01/2021 - 02/2014
9	Non-alcoholic Fatty Liver Disease 02/2024 - 11/2015
9	Vascular Remodeling 11/2023 - 10/2007
9	Glioma (Gliomas) 06/2023 - 10/2009
9	Carcinoma (Carcinomatosis) 01/2020 - 12/2003
8	Scoliosis 05/2024 - 07/2017
8	Melanoma (Melanoma, Malignant) 05/2023 - 01/2018
8	Liver Diseases (Liver Disease) 01/2023 - 04/2006
8	Sclerosing Cholangitis 01/2023 - 01/2016
8	Hypercholesterolemia 06/2019 - 03/2011
7	Glioblastoma (Glioblastoma Multiforme) 04/2024 - 04/2017
7	Body Weight (Weight, Body) 01/2023 - 04/2006
7	Acquired Hyperostosis Syndrome (SAPHO Syndrome) 04/2021 - 05/2018
6	Obesity 02/2024 - 02/2012
6	Chronic Obstructive Pulmonary Disease (COPD) 10/2023 - 01/2018
6	Enteritis 01/2023 - 01/2018
6	Hypertension (High Blood Pressure) 09/2022 - 10/2007
6	Leukemia 01/2020 - 05/2009
5	Squamous Cell Carcinoma (Epidermoid Carcinoma) 02/2024 - 12/2014
5	Type 2 Diabetes Mellitus (MODY) 01/2023 - 10/2012
5	Genomic Instability 01/2023 - 02/2012
5	Lymphatic Metastasis 03/2022 - 06/2007
5	Mitochondrial Diseases (Mitochondrial Disease) 01/2022 - 09/2011
5	Chronic Pancreatitis 01/2022 - 03/2016
5	Hyperplasia 01/2022 - 10/2017

Drug/Important Bio-Agent (IBA)

60	Proteins (Proteins, Gene)FDA Link 02/2024 - 10/2007
29	MicroRNAs (MicroRNA)IBA 10/2023 - 03/2011
25	Long Noncoding RNAIBA 02/2024 - 01/2018
24	Biomarkers (Surrogate Marker)IBA 02/2024 - 07/2007
19	Circular RNAIBA 04/2024 - 01/2017
16	Messenger RNA (mRNA)IBA 01/2023 - 06/2010
16	EnzymesIBA 01/2023 - 08/2008
15	CytokinesIBA 01/2023 - 01/2009
12	DNA (Deoxyribonucleic Acid)IBA 12/2022 - 07/2011
11	RNA (Ribonucleic Acid)IBA 12/2023 - 10/2014
11	CholesterolIBA 01/2023 - 03/2011
11	Transcription Factors (Transcription Factor)IBA 05/2022 - 06/2010
10	AntioxidantsIBA 04/2024 - 10/2007
10	LipidsIBA 01/2023 - 03/2011
9	Glucose (Dextrose)FDA LinkGeneric 02/2023 - 10/2012
9	Phosphotransferases (Kinase)IBA 10/2020 - 05/2009
8	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2023 - 01/2020
8	NF-kappa B (NF-kB)IBA 05/2022 - 10/2007
7	Indicators and Reagents (Reagents)IBA 04/2024 - 07/2002
7	Therapeutic UsesIBA 12/2023 - 10/2017
7	secretin receptorIBA 01/2023 - 01/2016
7	MelatoninIBA 01/2022 - 10/2017
7	triphenyltetrazoliumIBA 02/2021 - 05/2014
6	Small Interfering RNA (siRNA)IBA 01/2024 - 06/2017
6	Retinaldehyde (Retinal)IBA 12/2023 - 01/2009
6	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2023 - 09/2014
6	Tyrosine Kinase InhibitorsIBA 06/2023 - 02/2013
6	Cisplatin (Platino)FDA LinkGeneric 03/2023 - 05/2012
6	Doxorubicin (Adriamycin)FDA LinkGeneric 12/2022 - 09/2017
6	ParaffinIBA 12/2022 - 07/2005
6	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 02/2021 - 01/2009
6	CateninsIBA 10/2019 - 06/2017
6	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2015 - 07/2009
5	CollagenIBA 01/2024 - 01/2017
5	PlatinumIBA 12/2023 - 03/2013
5	Paclitaxel (Taxol)FDA LinkGeneric 12/2023 - 03/2013
5	Temozolomide (Temodar)FDA LinkGeneric 11/2023 - 06/2017
5	ErbB Receptors (EGF Receptor)IBA 06/2023 - 10/2020
5	Fatty Acids (Saturated Fatty Acids)IBA 01/2023 - 01/2019
5	Bile Acids and Salts (Bile Acids)IBA 01/2023 - 11/2021
5	Secretin FDA Link 01/2023 - 01/2016
5	Carrier Proteins (Binding Protein)IBA 12/2022 - 01/2018
5	Hormones (Hormone)IBA 01/2022 - 10/2017
5	Estrogen ReceptorsIBA 01/2022 - 12/2012
5	Adenosine Triphosphate (ATP)IBA 01/2022 - 10/2014

Therapy/Procedure

67	Therapeutics 02/2024 - 01/2011
28	Drug Therapy (Chemotherapy) 03/2024 - 01/2013
18	Immunotherapy 05/2024 - 06/2018
12	Lymph Node Excision (Lymph Node Dissection) 03/2022 - 06/2007
8	Radiotherapy 03/2024 - 11/2013
5	Vitrectomy 12/2023 - 01/2011
5	Neoadjuvant Therapy 01/2023 - 05/2017